Metformin protects against Clostridioides difficile infection by modulating both host and microbes
These data are raw data for Metabolites analysis with NMR, to demonstrate the effects of metformin on metabolism profile of C. difficile.
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metabolomics was performed in fecal samples extracted in water, as published elsewhere with minor changes (58). In brief, the extracted samples were mixed with a phosphate buffer (pH = 7.4), containing 10% D2O, 0.1 M phosphate, and 0.1 mM Trimethylsilyl propionate (TSP). The samples run on a Bruker Ascend 400 MHz high-resolution NMR instrument (Bruker Biospin, Germany), the NMR data acquired using a 1D first increment of a NOESY (noesygppr1d).