Metformin protects against Clostridioides difficile infection by modulating both host and microbes

Published: 19 May 2022| Version 1 | DOI: 10.17632/bc35n5p4th.1


These data are raw data for Metabolites analysis with NMR, to demonstrate the effects of metformin on metabolism profile of C. difficile.


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metabolomics was performed in fecal samples extracted in water, as published elsewhere with minor changes (58). In brief, the extracted samples were mixed with a phosphate buffer (pH = 7.4), containing 10% D2O, 0.1 M phosphate, and 0.1 mM Trimethylsilyl propionate (TSP). The samples run on a Bruker Ascend 400 MHz high-resolution NMR instrument (Bruker Biospin, Germany), the NMR data acquired using a 1D first increment of a NOESY (noesygppr1d).


University of South Florida


Nuclear Magnetic Resonance